期刊
PEDIATRIC BLOOD & CANCER
卷 52, 期 4, 页码 525-527出版社
WILEY
DOI: 10.1002/pbc.21751
关键词
aplastic anemia; childhood; cyclosporin A; gingival hyperplasia; tacrolimus
Aplastic anemia (AA) is a rare disorder in children, usually treated with immunosuppressive therapy (IST) including antithymocyte globulin (ATG) and cyclosporin A. There are no current widely used alternative therapies with comparable efficacy. We describe a child with severe aplastic anemia (SAA), who developed severe gingival hyperplasia secondary to cyclosporin A, unresponsive to intensive dental intervention. When IST was changed to tacrolimus there was a significant improvement in the gingival hyperplasia, but equally important, he achieved complete response of his AA within several months. The use of tacrolimus in children with AA may he a potential modality of treatment. Pediatr Blood Cancel 2009;52:525-527. (c) 2008 Wiley-Liss, Inc.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据