期刊
PARKINSONISM & RELATED DISORDERS
卷 17, 期 1, 页码 58-60出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.parkreldis.2010.10.002
关键词
Parkinson's disease; Handedness; Lateralization
The aim of this retrospective study was to assess the presence of a possible association between handedness and the side of symptom dominance in 963 patients with Parkinson's disease (PD). In only 287 patients the hand dominance was registered. Out of 254 right-handed patients, 158 (62%) had a right-side dominance of PD symptoms, while 96 patients (38%) had left-lateralized symptom dominance (p < 0.001). For the 33 left-handed subjects, 18 (55%) had left- and 15 (45%) had right-sided symptom dominance (p = 0.602). Right-handedness thus appeared to be associated with right-sided dominance of PD symptoms, while the group of left-handed patients was too small to draw conclusions from. Possible explanations are discussed. (C) 2010 Elsevier Ltd. All rights reserved.
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