期刊
PARKINSONISM & RELATED DISORDERS
卷 17, 期 5, 页码 379-381出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.parkreldis.2011.03.003
关键词
Parkinson's disease; Impulse-control disorder; Dopamine dysregulation; Valproate
Impulse-control disorders (ICDs) are becoming more commonly recognized in the Parkinson disease (PD) population. To date, there are no definitive methods of treating dopamine dysregulation syndromes in PD patients. We sought to uncover an effective treatment option for future study. We report a series of 3 PD patients with ICDs who were effectively treated with valproate. Based on these encouraging preliminary observations, future controlled clinical trials investigating the efficacy of valproate for ICDs in PD are recommended. (C) 2011 Elsevier Ltd. All rights reserved.
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