期刊
PARKINSONISM & RELATED DISORDERS
卷 14, 期 3, 页码 257-258出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.parkreldis.2007.04.006
关键词
Parkinson's disease; driving; dopamine dysregulation syndrome; impulsive disorders; risk taking
We report two male patients with Parkinson's disease who developed compulsive risk-seeking driving behaviour as a result of self-administering high doses of L-dopa despite an adequate therapeutic response at lower doses. When L-dopa reduction was feasible, it resulted in cessation of unsafe driving. We believe that this impairment in driving performance, due to deliberate overuse of dopaminergic medication, should be included as a new behavioural phenomenon in dopamine dysregulation syndrome. (c) 2007 Elsevier Ltd. All rights reserved.
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