期刊
PARASITOLOGY
卷 137, 期 2, 页码 241-249出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0031182009991090
关键词
Theileria; phylogeny; major piroplasm surface protein; gene sequences
类别
资金
- National Veterinary Research and Quarantine Service (NVRQS)
- Korea National Institute of Health (KNIH), Republic of Korea
To investigate the phylogeny of benign Theileria parasites, we determined the complete major piroplasm Surface protein (MPSP) gene sequences for 6 benign theilerial organisms, including the first from tick. Sequences were analysed alongside published sequences for 39 benign Theileria parasites, using Bayesian inference and maximum parsimony. All MPSP sequences were 852 nucleotides, except for Gansu, Wuchangbuf, VB01, and VB01; Gansu contained 873 nucleotides, and the other 3 had 855. Deduced amino acid sequences contained 284 residues, except for Gansu (291) and Wuchangbuf, VB01, and VB01 (285 each). Pairwise comparisons showed identities among 45 theilerial MPSP sequences ranging from 70.9 to 99.8% for nucleotide and 71.0 to 100% for amino acid sequences. Our results clearly indicate that all global parasites, excluding Brisbane, were classified into I of 8 types; 6 types of Theileria exist in Korea. Each type, excluding Type 6, has several type-specific amino acid sequences. The phylogenetic tree derived from the nucleotide sequences showed 2 sister-group relationships, Type 2 + Type 7 and Type 3 + Brisbane, with a new branching pattern: (Type 6 (Type 8 ((Type 2, Type 7), (Type 1, (Type 4, (Type 5, (Type 3, Brisbane))))))). Our sequence data showed no geographical influence on worldwide Theileria parasite distribution.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据