期刊
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
卷 66, 期 -, 页码 118-127出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2014.11.011
关键词
Analytical method; Chemical constituent; Cigarette smoke; Horwitz ratio; Nitrosamine; Performance standard; Regulatory testing; Reproducibility; Standardized method; Tobacco
资金
- British American Tobacco
This article includes a summary of the development of existing standardized methods to test cigarette smoke, and a review of both the capability of current methods for testing cigarette-smoke constituents and current performance standards relevant to regulatory testing. There is a comparison of the reproducibility of some currently approved methods to determine volatile constituents and tobacco-specific nitrosamines in cigarette smoke with the Horwitz prediction of reproducibility. There is discussion of appropriate activities to support the development and the implementation of more reproducible testing methods and an indication of the tasks that should be prioritized to achieve optimal inter-laboratory agreement of data. (C) 2014 The Author. Published by Elsevier B.V.
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