期刊
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
卷 66, 期 -, 页码 158-175出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2014.11.018
关键词
Blood; Breath; Chemical pattern; Emergency; Human VOCs; Odor; Skin; Trace detection; Urine; Volatile organic compound
资金
- European Community [217967]
- Austrian Federal Ministry for Transport, Innovation and Technology (BMVIT/BMWA) [836308]
- Oncotyrol-project 2.1.1
- Competence Centre Oncotyrol is funded within the scope of the COMET - Competence Centers for Excellent Technologies
- Austrian Science Fund (FWF) [P24736-B23]
- Government of Vorarlberg (Austria)
Since Pauling's paper in the 1970s, interest has increased in volatile organic compounds (VOCs) released from different bio-fluids, such as blood and urine. A number of VOCs reflect internal biochemical pathways occurring in the human body and their chemical pattern may serve as the chemical platform for tracing human VOCs. Monitoring endogenous human VOCs is proposed as an alternative method to the use of canines for search, rescue and emergency applications. Tracing human VOCs requires robust, rapid, reliable and sensitive analytical instruments. Instrumentation currently used to study human VOC biomarkers (e.g. GC-MS, PTR-MS, SIFT-MS, MCC-IMS, FAIMS and sensor based systems) has significant clinical potential, but has yet to receive widespread consideration for emergency search applications. (C) 2014 Elsevier B.V. All rights reserved.
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