期刊
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
卷 24, 期 3, 页码 232-240出版社
WILEY
DOI: 10.1111/j.1365-3016.2010.01113.x
关键词
maternal prenatal depression; child cognition; child visual motor abilities
资金
- National Institutes of Health [HD34568, HL69425, HL77504, HL68041]
We examined the association of prenatal depressive symptoms at mid-pregnancy with child cognition at age 3 years in Project Viva, a pre-birth cohort study of 1030 mother child pairs in eastern Massachusetts. We measured maternal depressive symptoms using the Edinburgh Postnatal Depression Scale (EPDS), a self-report measure validated for use during pregnancy. Measures of child cognition included the Peabody Picture Vocabulary Test (PPVT) and the Wide Range Achievement of Visual Motor Abilities (WRAVMA). At mid-pregnancy, 81 mothers (7.9%) scored 13 or above on the EPDS, indicating probable depression. In the unadjusted model, children born to mothers with prenatal depressive symptoms had PPVT scores that were 3.8 points lower [95% confidence interval (CI) -7.1, -0.5]. With adjustment for sociodemographic variables, the association substantially attenuated [adjusted regression coefficient b for PPVT score = -0.7 (95% CI -3.6, 2.3)]. In both unadjusted and multivariable models, prenatal depressive symptoms were not associated with WRAVMA scores [adjusted b for total WRAVMA score = -0.5 ( 95% CI -3.0, 2.1)]. We found no evidence to suggest that maternal prenatal depression is independently associated with early child cognition.
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