期刊
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
卷 33, 期 12, 页码 e119-e120出版社
WILEY-BLACKWELL PUBLISHING, INC
DOI: 10.1111/j.1540-8159.2010.02733.x
关键词
premature ventricular complexes (PVCs); ranolazine; non-sustained ventricular tachycardia (NSVT); ventricular tachycardia (VT); PVC cardiomyopathy
Premature ventricular complexes (PVCs) are a frequent occurrence in the presence of ischemic heart disease. A very high PVC load can be symptomatic or occasionally result in a cardiomyopathy (CMP). Treatment options include pharmacologic agents and radiofrequency ablation (RFA). RFA has been successful in treating PVCs in symptomatic patients or in the presence of unexplained CMP. Ranolazine is a piperazine derivative used for treating chronic stable angina. It also has antiarrhythmic properties. We report a patient with ischemic CMP, symptomatic PVCs, and monomorphic ventricular tachycardia (VT) despite attempts to control symptoms with two antiarrhythmic drugs. Initiation of ranolazine led to marked reduction in PVCs along with control of VT and symptoms. (PACE 2010; 33:e119-e120).
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