期刊
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
卷 146, 期 5, 页码 797-803出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0194599811433982
关键词
endolymphatic hydrops; Meniere disease; ocular vestibular-evoked myogenic potential; utriculo-endolymphatic valve
Objective. The asymmetry ratio of ocular vestibular-evoked myogenic potential (oVEMP) >40% is interpreted as augmented or reduced response depending on whether the nI-pI amplitude of the lesion ear is larger or smaller than that of the opposite ear, respectively. This study compared unilateral Meniere disease patients with augmented oVEMPs vs reduced oVEMPs to elucidate the mechanism of augmented oVEMP. Study Design. Case series with chart review. Setting. University hospital. Methods. Forty patients with unilateral definite Meniere disease were enrolled in this study, including 20 patients with augmented oVEMPs and another 20 patients with reduced oVEMPs in the hydropic side. All patients underwent audiometry, caloric test, and oVEMP and cervical VEMP (cVEMP) tests via bone-conducted vibration stimuli. Then, the oVEMP and cVEMP test results were compared with the stage of Meniere disease, respectively. Results. The augmented group had earlier nI and pI latencies and larger nI-pI amplitude of oVEMPs compared with the reduced group. Caloric test also revealed a significant difference in abnormal responses between the augmented and reduced groups. However, both groups did not differ significantly in the abnormal percentage of cVEMP test results. A significant trend to decline in the prevalence of augmented oVEMPs was noted from stages I to III-IV but not in that of abnormal cVEMPs. Conclusion. The augmented oVEMPs have earlier latencies and larger amplitudes compared with the reduced oVEMPs, indicating that a relatively larger population of intact utricular afferents is activated during the early stage of Meniere disease.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据