期刊
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
卷 148, 期 1, 页码 121-127出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0194599812464475
关键词
sudden sensorineural hearing loss; outpatient; treatment; steroid; dexamethasone; hearing
Objectives. We treated patients with idiopathic sudden sensorineural hearing loss (ISSNHL) with several protocols on an outpatient department (OPD) basis. The study compared the efficacy of 3 different steroid treatments for ISSNHL. Study Design. A prospective randomized controlled study. Setting. Tertiary referral center. Methods. A total of 60 patients diagnosed with ISSNHL were treated through OPD. They were randomly and equally divided into 3 groups based on therapy: oral steroid for 10 days (group I), intratympanic dexamethasone injection (ITDI) 4 times (group II), and both (group III). Pure-tone average (PTA) was measured by taking 4 frequencies (0.5, 1, 2, and 3 kHz). Hearing change was evaluated by comparing pre- and post-treatment PTAs. Recovery rate was assessed by American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) Clinical Practice Guidelines. Results. The hearing gain was 12.8 +/- 15.4 decibels (dB) in group I, 12.1 +/- 14.6 dB in group II, and 21.9 +/- 26.2 dB in group III. The recovery rate was 60% in groups I and III and 55% in group II. The overall recovery rate was 58.3% (35 of 60 patients). There was no significant difference in hearing gain and recovery rates for the 3 groups. Frequency-specific hearing gain also did not differ significantly among groups. Conclusion. Three different treatment protocols (oral steroid, ITDI, or the combination) resulted in similar hearing recovery rates. Therefore, OPD-based systemic and/or local steroid therapy can be recommended as an initial treatment in ISSNHL.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据