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Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1β secretion
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Crystal structure of the ATP-gated P2X4 ion channel in the closed state
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P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis
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Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment
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Human P2X7 pore function predicts allele linkage disequilibrium
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A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages
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A His-155 to Tyr polymorphism confers gain-of-function to the human P2X7 receptor of human leukemic lymphocytes
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A 5′intronic splice site polymorphism leads to a nulll allele of the P2X7 gene in 1-2% of the Caucasian population
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Extracellular nucleotides act through P2X7 receptors to activate NF-κB in osteoclasts
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An Arg307 to Gln polymorphism within the ATP-binding site causes loss of function of the human P2X7 receptor
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Blockade of the pore-forming P2X7 receptor inhibits formation of multinucleated human osteoclasts in vitro
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Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption
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An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor
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Glu496 Ala polymorphism of human P2X7 receptor does not affect its electrophysiological phenotype
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Intercellular calcium signaling occurs between human osteoblasts and osteoclasts and requires activation of osteoclast P2X7 receptors
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Activity-dependent development of P2X7 current and Ca2+ entry in rabbit osteoclasts
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Expression of a P2X7 receptor by a subpopulation of human osteoblasts
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A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor
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