期刊
TOXICOLOGY IN VITRO
卷 30, 期 1, 页码 4-6出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tiv.2014.09.016
关键词
Predict-IV; Systems toxicology; Cellular models; Liver; Kidney; Central nervous system (CNS)
类别
资金
- EU [20222]
This special issue of Toxicology in Vitro is dedicated to disseminating the results of the EU-funded collaborative project Profiling the toxicity of new drugs: a non animal-based approach integrating toxicodynamics and biokinetics (Predict-IV; Grant 202222). The project's overall aim was to develop strategies to improve the assessment of drug safety in the early stage of development and late discovery phase, by an intelligent combination of non animal-based test systems, cell biology, mechanistic toxicology and in silica modeling, in a rapid and cost effective manner. This overview introduces the scope and overall achievements of Predict-IV. (C) 2014 Elsevier Ltd. All rights reserved.
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