期刊
OSTEOARTHRITIS AND CARTILAGE
卷 22, 期 1, 页码 104-110出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.joca.2013.10.019
关键词
Magnetic resonance imaging; Population-based cohort; Intervertebral disc degeneration; Entire spine; Prevalence; Distribution
资金
- Japanese Ministry of Education, Culture, Sports, Science and Technology [19659305]
- Ministry of Health, Labour and Welfare, Research [H17-Men-eki-009, H18-Choujyu-037, H20-Choujyu-009]
- Japanese Orthopaedic Association
- Japanese Orthopaedics and Traumatology Foundation, Inc. [166]
- Japanese Society for the Promotion of Science [C22591639]
- [B20390182]
- [B23390357]
- [C20591737]
- [C20591774]
Objectives: The purposes of this study were to investigate the prevalence and distribution of intervertebral disc degeneration (DD) over the entire spine using magnetic resonance imaging (MRI), and to examine the factors and symptoms potentially associated with DD. Design: This study included 975 participants (324 men, mean age of 67.2 years; 651 women, mean age of 66.0 years) with an age range of 21-97 years in the Wakayama Spine Study. DD on MRI was classified into Pfirrmann's system (grades 4 and 5 indicating DD). We assessed the prevalence of DD at each level in the cervical, thoracic, and lumbar regions and the entire spine, and examined DD-associated factors and symptoms. Results: The prevalence of DD over the entire spine was 71% in men and 77% in women aged <50 years, and >90% in both men and women aged >50 years. The prevalence of an intervertebral space with DD was highest at C5/6 (men: 51.5%, women: 46%), T6/7 (men: 32.4%, women: 37.7%), and L4/5 (men: 69.1%, women: 75.8%). Age and obesity were associated with the presence of DD in all regions. Low back pain was associated with the presence of DD in the lumbar region. Conclusion: The current study established the baseline data of DD over the entire spine in a large population of elderly individuals. These data provide the foundation for elucidating the causes and mechanisms of DD. (C) 2013 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据