Effect of a glucosamine derivative on impact-induced chondrocyte apoptosis in vitro. A preliminary report

Here, we report that a lipophilic derivative of glucosamine, Glu5, is able to prevent impact-induced chondrocyte death by the putative mechanism of reducing mitochondrial depolarisation following a single impact load in vitro. (c) 2007 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.