期刊
ORGANOMETALLICS
卷 33, 期 16, 页码 4230-4239出版社
AMER CHEMICAL SOC
DOI: 10.1021/om500499s
关键词
-
资金
- Zhejiang Provincial Natural Science Foundation [LY13B020007]
- National Natural Science Foundation of China [21002073, 21372178]
- Graduate Innovation Foundation of Wenzhou University
The gold(I)-catalyzed alkenyl-, allyl-, and arylsilylation reactions of silyl-tethered enynes discovered by Murakami et al. provide efficient methods for the facile constructions of 1-silaindene derivatives. A comprehensive mechanistic DFT study of these reactions was carried out to better understand the experimental outcomes, and divergent and substrate-dependent mechanisms for the formations of 1-silaindene derivatives were uncovered based on the computational results. From cationic gold(I) pi-alkyne complexes, the endo-dig cyclization pathway may lead possibly to both C-2- and C-3-group-substituted (group = alkenyl, allyl, or aryl) 1-silaindene products, and the regioselectivity will be finally determined by the 1,2-group migration of the gold carbenoid intermediate. On the other hand, the exo-dig cyclization pathway leads only to C-3-group-substituted (group = alkenyl, allyl, or aryl) 1-silaindene, in which a notable promoting effect of the bistriflimide counterion on the rearrangement of the silyl cation intermediate was disclosed. The results reported herein provide insights into aspects of regioselective cyclization, silyl-involved skeletal rearrangements, chemoselective 1,2-migration in gold carbenoids, and the dramatic counterion effect in the reactions concerned.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据