4.5 Review

Challenges and Opportunities in the Development of Organometallic Anticancer Drugs

期刊

ORGANOMETALLICS
卷 31, 期 16, 页码 5677-5685

出版社

AMER CHEMICAL SOC
DOI: 10.1021/om300373t

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资金

  1. University of Auckland
  2. University of Vienna
  3. Austrian Science Fund
  4. Johanna Mahlke geb. Obermann Foundation
  5. Deutsche Forschungsgemeinschaft (DFG) through the research unit Biological Function of Organometallic Compounds (FOR 630)
  6. Ruhr-University Bochum
  7. Swiss National Science Foundation
  8. COST (Switzerland), EPFL
  9. EU
  10. COST action D39 Metallodrug Design and Action

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This review provides an introduction into the fascinating area of organometallic anticancer compounds. Although the subject dates back many years, it has witnessed considerable growth only in the past decade. A brief overview of the subject together with recent pertinent examples is provided. The properties of organometallic compounds that lend themselves to medical applications, the main current approaches used, and possible avenues for future research are identified.

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