Titanacarborane amide catalyzed transamination of guanidines

This work describes a catalytic transamination of guanidines with a broad substrate scope of primary, secondary, heterocyclic, aliphatic, and aromatic amines, using 5-10 mol % of the half-sandwich titanacarborane amide [sigma:eta(1):eta(5)-(OCH2)-(Me2NCH2)C2B9H9]Ti(NMe2) as catalyst. This reaction tolerates common functional groups. The reaction mechanism is also proposed.