4.6 Article

Sanofi's Solvent Selection Guide: A Step Toward More Sustainable Processes

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ORGANIC PROCESS RESEARCH & DEVELOPMENT
卷 17, 期 12, 页码 1517-1525

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AMER CHEMICAL SOC
DOI: 10.1021/op4002565

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Sanofi's solvent selection guide helps chemists in early development select sustainable solvents that will be accepted in all production sites. Solvents are divided into four classes, from recommended to banned. This ranking is derived from Safety, Health, Environmental, Quality, and Industrial constraints. Each solvent has its own ID card that indicates the overall ranking, H, S & E hazard bands, as well as its ICH limit, physical properties, cost, and substitution advice.

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