期刊
ORGANIC PROCESS RESEARCH & DEVELOPMENT
卷 16, 期 5, 页码 741-747出版社
AMER CHEMICAL SOC
DOI: 10.1021/op300002f
关键词
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The intramolecular Diels-Alder reaction provides a useful synthetic methodology to build biologically active and synthetically useful isoindolone ring systems. An application of this methodology, providing an efficient manufacturing route to an mGluR2 positive allosteric modulator via a 1,5,7-substituted isoindolone, is reported herein.
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