期刊
ORGANIC LETTERS
卷 16, 期 16, 页码 4324-4327出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol5020619
关键词
-
资金
- Japan Society for the Promotion of the Science [25450145]
- Japan Society for the Promotion of Science Fellowships for young scientists [8696]
- Grants-in-Aid for Scientific Research [25450145, 12J08696] Funding Source: KAKEN
Total synthesis of callipeltins B and M, peptidyl cytotoxic agents isolated from marine sponges, by the combination of Fmoc solid-phase peptide synthesis and cyclization and global deprotection in the solution phase is described. Eight amino acids, including several unusual amino acids, were assembled on a solid support, and effective TFA-mediated deprotection was employed to reach callipeltin M. Callipeltin B was accomplished via the macrolactonization between the side chain of D-aThr and the C-terminus carboxylic acid of protected callipeltin M.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据