期刊
ORGANIC LETTERS
卷 16, 期 6, 页码 1740-1743出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol500421k
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资金
- Estonian Ministry of Education and Research [JUT 19-32]
- EU European Regional Development Fund [3.2.0101.08-0017]
The concept of the remote activation of reactivity was first applied in asymmetric organocatalysis. An isatin 3-phenylimine derivative acts as a donor in the thiourea catalyzed asymmetric addition to unsaturated 1,4-ketoesters, affording aza-Michael adducts in high enantiomeric purity and yield.
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