4.8 Article

Squaramide Equilibrium Acidities in DMSO

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ORGANIC LETTERS
卷 16, 期 6, 页码 1786-1789

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AMER CHEMICAL SOC
DOI: 10.1021/ol5005017

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资金

  1. Most [2012CB821600, 2010CB833300]
  2. NSFC [21390400, 21172112, 21172118]
  3. State Key Laboratory on Elemento-organic Chemistry
  4. Program for New Century Excellent Talents in University [NCET-12-0279]

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A number of popular squaramide organocatalysts' acidities were determined by an overlapping indicator method in DMSO via UV spectrophotometric titrations. The pK(a) values are in the range of 8.37-16.46. The results may be helpful for the rational design and development of squaramide type new catalysts.

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