期刊
ORGANIC LETTERS
卷 16, 期 21, 页码 5528-5531出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol502003a
关键词
-
资金
- Australian Research Council Centre of Excellence for Free Radical Chemistry and Biotechnology [CE0561607]
- QUT
- Icelandic Research Fund [141062051]
- University of Iceland Research Fund
We report the synthesis of a new class of molecules which are hybrids of long-lived tetramethylisoindolinoxyl (TMIO) radicals and the pyrido[1,2-a]benzimidazole (PyrImid) scaffold. These compounds represent a new lead for noncovalently binding nucleic acid probes, as they interact with nucleic acids with previously unreported C (DNA) and C/U (RNA) complementarity, which can be detected by electron paramagnetic resonance (EPR) techniques. They also have promising properties for fluorimetric analysis, as their fluorescent spin-quenched derivatives exhibit a significant Stokes shift.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据