期刊
ORGANIC LETTERS
卷 16, 期 7, 页码 2062-2065出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol500667d
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-
资金
- National Natural Science Foundation of China (NSFC) [21072084, 21272099]
Ivorenolide B (1), an unprecedented 17-membered macrolide featuring conjugated acetylenic bonds and four chiral centers, was isolated from Khaya ivorensis. The structure of 1 was fully determined by spectroscopic analysis and total syntheses of its four most possible stereoisomers. Compound 1 showed significant immunosuppressive activity.
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