期刊
ORGANIC LETTERS
卷 15, 期 24, 页码 6262-6265出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol4031149
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资金
- IISc
- RL Fine Chem
- CSIR
A highly regioselective functionalization of indole at the C-4 position by employing an aldehyde functional group as a directing group, and Ru as a catalyst, under mild reaction conditions (open flask) has been uncovered. This strategy to synthesize 4-substituted indoles is important, as this class of privileged molecules serves as a precursor for ergot alkaloids and related heterocyclic compounds.
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