期刊
ORGANIC LETTERS
卷 15, 期 19, 页码 5036-5039出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol402370f
关键词
-
资金
- EPSRC
- EPSRC [EP/G007519/2] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/G007519/2] Funding Source: researchfish
A simple protocol for the difluoromethylation of thiols is reported using chlorodifluoroacetate as the difluoromethylating agent. This cheap reagent undergoes smooth decarboxylation at 95 degrees C to afford difluorocarbene, which can be trapped with a variety of aromatic and heteroaromatic thiols. The reaction is also effective for the difluoromethylation of heterocyclic nitrogen compounds and phenylselenol.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据