期刊
ORGANIC LETTERS
卷 15, 期 8, 页码 1846-1849出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol4004542
关键词
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资金
- National Basic Research Program of China [2009CB940903, 2009CB918502, 2012CB518005]
- NSFC [21021063, 91229204, 81025017]
- National S&T Major Projects [2012ZX09103-101-072]
- China-EU Science and Technology Cooperation Project [1109]
- Silver Project [260644]
An asymmetric organo- and gold-catalyzed one-pot sequential Mannich/hydroamination reaction has been developed. Using this protocol, spiro[pyrrolidin-3,2'-oxindole] derivatives were synthesized in good yields (up to 91%) and excellent enantioselectivities (up to 97% ee).
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