期刊
ORGANIC LETTERS
卷 15, 期 16, 页码 4242-4245出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol401932p
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资金
- National Science Council of Taiwan [NSC 101-2627-M-009-006]
- National Chiao Tung University
- Ministry of Education of Taiwan (Center for Bioinformatics Research of Aiming for the Top University Program)
A dansyl derivative (Ds-DAB) was prepared and used as a fluorescent probe for peroxynitrite (ONOO-) detection. The results showed that the addition of peroxynitrite to the aqueous solution of Ds-DAB would result in obvious fluorescence enhancement. This probe is highly specific for peroxynitrite in aqueous solution, avoiding interference from other reactive oxygen species (ROS) and nitrogen species (RNS). The advantages of high selectivity, fast reaction rate, and peroxynitrite bioimaging render Ds-DAB suitable for peroxynitrite detection.
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