期刊
ORGANIC LETTERS
卷 15, 期 14, 页码 3586-3589出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol401428x
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资金
- Bristol-Myers Squibb (BMS) Summer Intern Program
A multicomponent (single reactor) process for the synthesis of 1-aryl 1,2,4-triazoles was explored and developed. This transformation prepared the 1,2,4-triazole directly from anilines, amino pyridines, and pyrimidines. The reaction scope was explored with 21 different substrates, and the position of the nitrogen atoms in the newly formed ring was established by N-15 labeling and NMR spectroscopy.
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