期刊
ORGANIC LETTERS
卷 15, 期 18, 页码 4896-4899出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol402346c
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资金
- National Basic Research Program of China (973 Program) [2010CB833300]
- National Natural Science Foundation of China [21172112, 21172118]
- Program for New Century Excellent Talents in University [NCET-12-0279]
A highly enantioselective Michael aldol tandem reaction with respect to prochiral 2-substituted benzofuran-3-ones and enones by a facile primary amine catalyst was investigated. The approach provides rapid access to the desired pharmaceutically active griseofulvin analogues.
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