4.8 Article

Sultam Synthesis via Cu-Catalyzed Intermolecular Carboamination of Alkenes with N-Fluorobenzenesulfonimide

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ORGANIC LETTERS
卷 15, 期 10, 页码 2502-2505

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AMER CHEMICAL SOC
DOI: 10.1021/ol4009848

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资金

  1. ACT-C program from JST
  2. MEXT
  3. JSPS
  4. Grants-in-Aid for Scientific Research [25105712] Funding Source: KAKEN

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Cu-catalyzed intermolecular carboamination of alkenes is described. The reaction of terminal alkenes and an internal alkene with N-fluorobenzenesulfonimide was promoted by 2.5 mol % of a Cu(I)-salt at 60 degrees C, and six-membered ring sultams were obtained in 91-44% yields.

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