期刊
ORGANIC LETTERS
卷 15, 期 13, 页码 3306-3309出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol4013958
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资金
- EPSRC [EP/G068313/1]
- University of York
- EPSRC [EP/G068313/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/G068313/1] Funding Source: researchfish
The first total synthesis of spirobacillene A, an indole alkaloid isolated from Lysinibacillus fusiformis, is reported. A Lewis acid mediated spirocyclization of an anisole derivative onto a tethered ynone was used as a key step, drawing inspiration from a potential biosynthesis of the natural product.
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