期刊
ORGANIC LETTERS
卷 15, 期 8, 页码 2030-2033出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol400720b
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资金
- EPSRC [EP/H015078]
- Pfizer
- EPSRC [EP/H015078/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/H015078/1] Funding Source: researchfish
The cycloaddition of chiral tert-butanesulfinimines with trimethylenemethane is found to give facile access to methylene-pyrrolidines with good yields and diastereoselectivities. The full scope of the cycloaddition is explored, and a range of transformations of the formed methylenepyrrolidines to give a range of functionalized chiral pyrrolidines is presented.
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