期刊
ORGANIC LETTERS
卷 15, 期 13, 页码 3456-3459出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol401495c
关键词
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资金
- Swiss National Science Foundation
- Ecole Polytechnique Federale de Lausanne (EPFL)
A coumarin-based molecular probe can be used for the sensing of peptides and aminoglycoside antibiotics. The probe reacts with the primary amine group(s) of the analytes to give a mixture of covalent adducts with distinct colors. Each analyte gives rise to a characteristic UV-vis spectrum. A pattern-based analysis of the spectra allows identifying structurally related analytes. Furthermore, it is possible to obtain information about the quantity and the purity of the analytes.
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