Catalytic Asymmetric Synthesis of Cyclic Sulfamides from Conjugated Dienes

This paper describes the catalytic asymmetric diamination of alkyl dienes using N,N-di-tert-butylthiadiaziridine 1,1-dioxide In the presence of Pd(0) and a chiral phosphoramidite ligand to give cyclic sulfamides in high yield and high ee. The diamination is also amenable to gram scale.