4.8 Article

Pd(II)-Catalyzed Sequential C-C/C-O Bond Formations: A New Strategy to Construct Trisubstituted Furans

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ORGANIC LETTERS
卷 15, 期 8, 页码 1838-1841

出版社

AMER CHEMICAL SOC
DOI: 10.1021/ol400451t

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资金

  1. National Natural Science Foundation of China [20932002, 21172076, 21202046]
  2. National Basic Research Program of China (973 Program) [2011CB808600]
  3. Guangdong Natural Science Foundation [10351064101000000, S2012040007088]
  4. China Postdoctoral Science Foundation [2012T50673]
  5. Fundamental Research Funds for the Central Universities [2012ZP0003, 2012ZB0011]

向作者/读者索取更多资源

Palladium-catalyzed oxidative difunctionalization of enol ethers with 1,3-dicarbonyl compounds to construct trisubstituted furans in one step under mild conditions is described. The reaction is thought to proceed through a C-C bond formation along with a C-O bond closing the ring structure. Oxygen is the sole oxidant regenerating the Pd(II) catalyst.

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