4.8 Article

Palladium-Catalyzed Conjugate Addition of Terminal Alkynes to Enones

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ORGANIC LETTERS
卷 14, 期 12, 页码 2996-2999

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AMER CHEMICAL SOC
DOI: 10.1021/ol300988n

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资金

  1. Spanish MINECO [SAF2007-61015, SAF2010-20822-C02, CSD2007-00006]
  2. ERDF
  3. Xunta de Galicia [INCITE09209084PR, GRC2010/12]
  4. Spanish MEC
  5. MINECO

向作者/读者索取更多资源

A practical protocol for the hydroalkynylation of enones using Pd catalysis is reported. The reaction proceeds efficiently with a variety of alkynes as well as with several cyclic and acyclic enones, providing synthetically relevant beta-alkynyl ketones in good to excellent yields.

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