期刊
ORGANIC LETTERS
卷 14, 期 7, 页码 1764-1767出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol300359s
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资金
- Syracuse University
A facile synthesis of imidazo[4,5-b]pyridines and -pyrazines is described using a Pd-catalyzed amide coupling reaction. This reaction provides quick access to products with substitution at N1 and C2. A model system relevant to the natural product pentosidine has been demonstrated, as well as the total synthesis of the mutagen 1-Me-5-PhIP.
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