A Synthetic Method for Palladium-Catalyzed Stannylation at the 5-and 6-Benzo Positions of Indoles

The stannylation of indole derivatives proceeds in good yields under palladium catalysis (5 mol %) without protection of the indolic nitrogen. The general utility of both PdCl2(PhCN)(2)/PCy3 and Pd(2)dba(3)/PCy3 as catalytic systems for the stannylation of three indole derivatives, with varying degrees of electron density, is presented.