Catalytic Radical Cation Salt Induced Csp3-H Functionalization of Glycine Derivatives: Synthesis of Substituted Quinolines

A domino C-sp3-H functionalization of glycine derivatives was achieved under catalytic radical cation salt induced conditions, producing a series of quinolines. The proposed mechanism shows that a peroxyl radical cation, which is generated by the coupling between O-2 and TBPA(+center dot), might be involved to initiate the catalytic oxidation.