4.8 Article

Nickel-Catalyzed Intermolecular Insertion of Aryl Iodides to Nitriles: A Novel Method to Synthesize Arylketones

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卷 14, 期 5, 页码 1282-1285

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AMER CHEMICAL SOC
DOI: 10.1021/ol300153f

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  1. National Science Council of the Republic of China [NSC-99-2113-M-032-003-MY2]

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A novel procedure for the NiCl2(DME)/dppp/Zn system catalyzed intermolecular insertion of aryl iodides to nitriles was developed, which afforded variously substituted arylketone derivatives in moderate to good yields with tolerance of a wide variety of functional groups.

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