期刊
ORGANIC LETTERS
卷 14, 期 16, 页码 4242-4245出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol301956p
关键词
-
资金
- NIH [R01 GM081376]
A library of benzimidazole-substituted potassium organotrifluoroborates was prepared via the condensation of various potassium formyl-substituted aryl- and heteroaryltrifluoroborates with aromatic 1,2-diamines under oxidative conditions. The efficient Suzuki-Miyaura cross-coupling of products thus formed to various aryl and heteroaryl bromides was achieved in good yields. The method allows the facile preparation of benzimidazole-containing triaromatic products in two steps from simple potassium formyl substituted aryl- or heteroaryltrifluoroborates.
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