期刊
ORGANIC LETTERS
卷 14, 期 4, 页码 1164-1167出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol300125s
关键词
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资金
- MEXT, Japan [22750101]
- Eno Foundation for the Promotion of Science
- Grants-in-Aid for Scientific Research [23245031, 22750101] Funding Source: KAKEN
Intramolecular 1,3-dipolar cycloaddition of 2-phenoxybenzonitrile N-oxides to benzene rings, accompanied by dearomatization, formed the corresponding isoxazolines in high yields. The X-ray single-crystal structure analysis revealed that the reaction formed the cis-adduct as a single isomer. The substituents on the benzene rings markedly affected the reaction rate, yield, and structure of the final product.
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