期刊
ORGANIC LETTERS
卷 14, 期 12, 页码 2948-2951出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol301214u
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资金
- Pennsylvania State University
- U.S. National Science Foundation [CHE-1055795]
- Division Of Chemistry
- Direct For Mathematical & Physical Scien [1055795] Funding Source: National Science Foundation
An efficient functionalization of ortho-C(sp(2))-H bonds of picolinamide (PA)-protected benzylamine substrates with a range of vinyl iodides as well as acetylenic bromide is reported. ortho-Phenyl benzoic acid (oPBA) acts as an effective promoter in this reaction system. This method provides a practical strategy to access highly functionalized benzylamine compounds for organic synthesis.
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