4.8 Article

Pyridine Ligands as Promoters in PdII/0-Catalyzed C-H Olefination Reactions

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ORGANIC LETTERS
卷 14, 期 7, 页码 1760-1763

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AMER CHEMICAL SOC
DOI: 10.1021/ol300281p

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  1. NSF through the Center for Enabling New Technologies through Catalysis (CENTC)
  2. DFG (German Research Council) [EM 219/1-1]

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Commercially available pyridine ligands can significantly enhance the rate, yield, substrate scope, and site selectivity of arene C-H olefination (Fujiwara-Moritani) reactions. The use of a 1:1 ratio of Pd/pyridine proved critical to maximize reaction rates and yields.

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