期刊
ORGANIC LETTERS
卷 14, 期 18, 页码 4810-4813出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol302119j
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资金
- AstraZeneca
- Ministry of Education, Singapore
- Swiss National Science Foundation
- BP Endowment
A highly efficient and enantioselective synthesis of 3-amino-2-oxindoles through a palladium-catalyzed asymmetric intramolecular arylation of alpha-ketimino amides using (R)-DiFluorPhos as the coordinating ligand is reported. This report constitutes the first enantioselective palladium. catalyzed arylation of ketimines.
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