期刊
ORGANIC LETTERS
卷 14, 期 14, 页码 3656-3659出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol301496m
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资金
- GSK
- EPSRC
- University of Bath
The oxidation of alkyl and aryl aldehydes to their corresponding carboxylic acids has been achieved through the action of a biomimetic bridged flavin catalyst. The reaction uses readily available 35% aqueous hydrogen peroxide and is operationally simple. The oxidation is a green and sustainable reaction, obviating chlorinated solvents with minimal byproducts.
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