期刊
ORGANIC LETTERS
卷 15, 期 2, 页码 398-401出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol303388k
关键词
-
资金
- National Institutes of Health [GM 74776]
- Stony Brook University
A 12-step synthesis of kingianin A, an inhibitor of the antiapoptotic protein Bcl-xL, Is based on a radical cation Diels-Alder reaction (RCDA). This approach is thought to be biomimetic. The use of a tether in the key RCDA step controls the regiochemistry of the cycloaddition, leading to the desired core structure and a separable diastereomer.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据