期刊
ORGANIC LETTERS
卷 14, 期 9, 页码 2258-2261出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol300659d
关键词
-
资金
- Shanghai Institute of Organic Chemistry
- Chinese Academy of Sciences
- State Key Laboratory of BioOrganic and Natural Products Chemistry
A series of novel P-chiral monophosphorus ligands exhibit efficiency in asymmetric Suzuki-Miyaura coupling reactions, enabling the construction of an array of chiral biaryl products In high yields and excellent enantioselectivities (up to 96% ee) under mild conditions. The carbonyl-benzooxazolidinone moiety in these chiral biaryl products allows facile derivatization for further synthetic applications. A computational study has revealed that a pi-pi interaction between the two coupling partners can enhance the enantioselectivity of the coupling reaction.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据